Invention Application
US20060019997A1 Triazole compounds and their use as metabotropic glutamate receptor antagonists
审中-公开
三唑化合物及其作为代谢型谷氨酸受体拮抗剂的用途
- Patent Title: Triazole compounds and their use as metabotropic glutamate receptor antagonists
- Patent Title (中): 三唑化合物及其作为代谢型谷氨酸受体拮抗剂的用途
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Application No.: US11060366Application Date: 2005-02-18
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Publication No.: US20060019997A1Publication Date: 2006-01-26
- Inventor: Louise Edwards , Methvin Isaac , Martin Johansson , Johan Malmberg , Alexander Minidis , Karin Staaf , Abdelmalik Slassi , David Wensbo , Tomislav Stefanac , Tao Xin
- Applicant: Louise Edwards , Methvin Isaac , Martin Johansson , Johan Malmberg , Alexander Minidis , Karin Staaf , Abdelmalik Slassi , David Wensbo , Tomislav Stefanac , Tao Xin
- Assignee: AstraZeneca AB,NPS Pharmaceuticals Inc.
- Current Assignee: AstraZeneca AB,NPS Pharmaceuticals Inc.
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; A61K31/4196 ; A61K31/4245 ; C07D413/14 ; C07D403/14

Abstract:
The present invention relates to new compounds of formula I, wherein P, Q, X1, X2, X3, X4 X7, X8, R1, R2, R3, m, n, and p are as defined as in formula I, or salts, or hydrates thereof, processes for their preparation and new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and to the use of said compounds in therapy.
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