发明申请
- 专利标题： Bicyclic heterocycles as HIV integrase inhibitors
- 专利标题（中）： 双环杂环作为HIV整合酶抑制剂
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申请号： US11126891申请日： 2005-05-11
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公开(公告)号： US20050267105A1公开(公告)日： 2005-12-01
- 发明人: B. Naidu , Jacques Banville , Francis Beaulieu , Timothy Connolly , Mark Krystal , John Matiskella , Carl Ouellet , Serge Plamondon , Roger Remillard , Margaret Sorenson , Yasutsugu Ueda , Michael Walker
- 申请人： B. Naidu , Jacques Banville , Francis Beaulieu , Timothy Connolly , Mark Krystal , John Matiskella , Carl Ouellet , Serge Plamondon , Roger Remillard , Margaret Sorenson , Yasutsugu Ueda , Michael Walker
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; A61K31/538 ; A61P31/18 ; C07D491/04 ; C07D498/04
摘要：
The invention encompasses a series cyclic bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
公开/授权文献
- US07176196B2 Bicyclic heterocycles as HIV integrase inhibitors 公开/授权日：2007-02-13
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