发明申请
US20050227287A1 Chaperones capable of binding to prion proteins and distinguishing the isoforms PrPc and PrPSc
审中-公开
分子伴侣能够结合朊病毒蛋白并区分同种型PrPc和PrPSc
- 专利标题： Chaperones capable of binding to prion proteins and distinguishing the isoforms PrPc and PrPSc
- 专利标题（中）： 分子伴侣能够结合朊病毒蛋白并区分同种型PrPc和PrPSc
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申请号： US10106825申请日： 2002-03-27
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公开(公告)号： US20050227287A1公开(公告)日： 2005-10-13
- 发明人: Ernst-Ludwig Winnacker , Stefan Weiss , Frank Edenhofer , Roman Rieger
- 申请人： Ernst-Ludwig Winnacker , Stefan Weiss , Frank Edenhofer , Roman Rieger
- 优先权： DEEP96107677.5 19960514
- 主分类号： G01N33/566
- IPC分类号： G01N33/566 ; A61K38/00 ; A61K38/17 ; A61K38/45 ; A61K38/46 ; A61K39/395 ; A61K45/00 ; A61P25/28 ; C07K1/14 ; C07K14/47 ; C07K16/18 ; C07K19/00 ; C12N5/10 ; C12N15/09 ; C12P21/08 ; C12Q1/68 ; G01N33/68 ; G01N33/53 ; C12Q1/37
摘要：
The present invention relates to methods for the detection or isolation of prion proteins by use of chaperones specifically binding to said proteins. The invention further relates to a method for in-vitro diagnosis of a transmissible spongiform encephalopathy and to pharmaceutical compositions, preferably for the prevention or treatment of said disease.
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