发明申请
- 专利标题： Method for screening agents for the treatment of diabetes
- 专利标题（中）： 用于治疗糖尿病的筛选剂的方法
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申请号： US10975367申请日： 2004-10-29
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公开(公告)号： US20050136484A1公开(公告)日： 2005-06-23
- 发明人: Takahide Ohishi , Jun Takasaki , Mitsuyuki Matsumoto , Tetsu Saito , Masazumi Kamohara , Takatoshi Soga , Shigeru Yoshida , Yoshitaka Ueda
- 申请人： Takahide Ohishi , Jun Takasaki , Mitsuyuki Matsumoto , Tetsu Saito , Masazumi Kamohara , Takatoshi Soga , Shigeru Yoshida , Yoshitaka Ueda
- 专利权人： Yamanouchi Pharmaceutical Co., Ltd.
- 当前专利权人： Yamanouchi Pharmaceutical Co., Ltd.
- 优先权： JP2000-367349 20001201; JP2001-243841 20010810
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61P3/10 ; A61P43/00 ; C07K14/705 ; C07K14/72 ; C12N1/15 ; C12N1/19 ; C12N1/21 ; C12N15/12 ; G01N33/53
摘要：
A convenient screening tool and a convenient screening method for obtaining an agent for treating diabetes, a pharmaceutical composition for treating diabetes, and a process for manufacturing the pharmaceutical composition are disclosed. The screening tool is a G protein-coupled receptor, a variation functionally equivalent thereto, or a homologous polypeptide thereof which promotes insulin secretion under a high glucose concentration by activation, or cells transformed with an expression vector comprising a polynucleotide encoding the above polypeptide and expressing the polypeptide.
公开/授权文献
- US07662775B2 Method for screening agents for the treatment of diabetes 公开/授权日：2010-02-16
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