Invention Application
US20050034280A1 Alpha-helical protein based materials and methods for making same
失效
基于α-螺旋蛋白的材料及其制备方法
- Patent Title: Alpha-helical protein based materials and methods for making same
- Patent Title (中): 基于α-螺旋蛋白的材料及其制备方法
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Application No.: US10917376Application Date: 2004-08-13
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Publication No.: US20050034280A1Publication Date: 2005-02-17
- Inventor: John Gosline , Douglas Fudge , Paul Guerette
- Applicant: John Gosline , Douglas Fudge , Paul Guerette
- Applicant Address: CA Vancouver
- Assignee: The University of British Columbia
- Current Assignee: The University of British Columbia
- Current Assignee Address: CA Vancouver
- Main IPC: D01F4/00
- IPC: D01F4/00 ; A61K38/00 ; B28B11/18 ; D01H5/00

Abstract:
The invention relates to a method of producing useful materials from filament-forming α-helical proteins or filaments made of such proteins. The method comprises allowing filament-forming α-helical proteins to self-assemble into α-helix containing filaments and forming fibres, films or bulk materials from the filaments. The materials are stretched to strain the filaments so that the α-helices substantially irreversibly change to β-sheet forms. The filament-forming α-helical proteins can comprise intermediate filament proteins. In a specific embodiment, the filament-forming proteins comprise hagfish slime thread IF proteins.
Public/Granted literature
- US07049405B2 α-helical protein based materials and methods for making same Public/Granted day:2006-05-23
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