Invention Grant
- Patent Title: Nucleic acid amplification assays for detection of pathogens
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Application No.: US16328548Application Date: 2017-08-25
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Publication No.: US12209292B2Publication Date: 2025-01-28
- Inventor: Mary Lynn Baniecki , Hayden Metsky , Pardis Sabeti
- Applicant: THE BROAD INSTITUTE, INC. , MASSACHUSETTS INSTITUTE OF TECHNOLOGY , PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Applicant Address: US MA Cambridge; US MA Cambridge; US MA Cambridge
- Assignee: THE BROAD INSTITUTE, INC.,MASSACHUSETTS INSTITUTE OF TECHNOLOGY,PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee: THE BROAD INSTITUTE, INC.,MASSACHUSETTS INSTITUTE OF TECHNOLOGY,PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee Address: US MA Cambridge; US MA Cambridge; US MA Cambridge
- Agency: Johnson, Marcou, Isaacs & Nix, LLC
- Agent F. Brent Nix, Esq.; Erin M. Daly
- International Application: PCT/US2017/048744 WO 20170825
- International Announcement: WO2018/039640 WO 20180301
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6893 ; C12Q1/70 ; G16B30/00 ; G16B30/10
Abstract:
The present invention relates to a method for generating primers and/or probes for use in analyzing a sample which may comprise a pathogen target sequence comprising providing a set of input genomic sequence to one or more target pathogens, generating a set of target sequences from the set of input genomic sequences, identifying one or more highly conserved target sequences, and generating one or more primers, one or more probes, or a primer pair and probe combination based on the one or more conserved target sequences.
Public/Granted literature
- US20190194766A1 NUCLEIC ACID AMPLIFICATION ASSAYS FOR DETECTION OF PATHOGENS Public/Granted day:2019-06-27
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