A device for removal of bio-film without cutting or injury to tissue is provided which is an elongated, thin and flexible member which encases a fiber optic piece and having a downward curved section at or near one end. The fiber optic protrudes from the end of the member and is covered by a diffuser to create a light emitting head, which can be used to direct light energy to a selected treatment site. Disclosed are safe, simple and effective broad-spectrum treatments for bio-film removal, such as halitosis and other microbial infections of the non-dental upper respiratory tract useful to treat bacterial and other microorganism species, including anaerobic bacteria. Electromagnetic radiative energy including visible, and optionally, thermal, RF and/or microwave wavelengths, is topically applied to internal surfaces of the upper respiratory tract to destroy or incapacitate superficial microorganisms without the use of antibiotics.