Invention Grant
- Patent Title: NIR-conjugated tumor-specific antibodies and uses thereof
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Application No.: US18160202Application Date: 2023-01-26
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Publication No.: US12178887B2Publication Date: 2024-12-31
- Inventor: Paul Yazaki , Jack Shively , Michael Bouvet , Jonathan Delong , Yuman Fong
- Applicant: CITY OF HOPE , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Applicant Address: US CA Duarte; US CA Oakland
- Assignee: CITY OF HOPE,THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee: CITY OF HOPE,THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee Address: US CA Duarte; US CA Oakland
- Agency: Perkins Coie LLP
- Agent Lara J. Dueppen; Adeh Vartanian
- Main IPC: A61K49/00
- IPC: A61K49/00 ; A61B5/00 ; A61B6/03 ; A61B6/40 ; A61B34/20 ; A61K39/00 ; A61K51/10 ; C07K16/30

Abstract:
Disclosed is a tumor-specific antibody and fluorophore conjugate for detecting, localizing and imaging of various tumors. Also disclosed are methods for detecting, localizing and imaging a solid tumor before or during a tumor resection surgery using the antibody-fluorophore conjugate.
Public/Granted literature
- US20230241253A1 NIR-CONJUGATED TUMOR-SPECIFIC ANTIBODIES AND USES THEREOF Public/Granted day:2023-08-03
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