Invention Grant
- Patent Title: Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid
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Application No.: US17583994Application Date: 2022-01-25
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Publication No.: US12103930B2Publication Date: 2024-10-01
- Inventor: Rudolf Moser , Viola Groehn , Thomas Egger , Thomas Ammann
- Applicant: MERCK & CIE
- Applicant Address: CH Schaffhausen
- Assignee: MERCK & CIE
- Current Assignee: MERCK & CIE
- Current Assignee Address: CH Schaffhausen
- Agency: MILLEN, WHITE, ZELANO & BRANIGAN, P.C.
- Agent Csaba Henter
- The original application number of the division: US16796164 2020.02.20
- Main IPC: C07D475/12
- IPC: C07D475/12 ; A61K9/00 ; A61K9/08 ; A61K9/19 ; A61K31/282 ; A61K31/395 ; A61K31/4745 ; A61K31/519 ; A61K39/395 ; C07D475/04
Abstract:
The invention is directed towards stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid and its hemisulfate salt as well as pharmaceutical compositions and uses thereof in therapy, preferably chemotherapy.
Public/Granted literature
- US20220143027A1 Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid Public/Granted day:2022-05-12
Information query
