A vehicle cargo utilization control system includes a processor disposed in a vehicle controller and a memory for storing executable instructions. The processor is programmed to execute the instructions to receive identity information associated with a vehicle user from a mobile device and vehicle sensory devices, and determine identity of the vehicle user. The system receives receive anthropometry information, and entry and exit data associated with the vehicle user that can indicate mobility limitations or special uses of the vehicle cargo hold that have been observed and recorded by the system. The processor may determine a vehicle recommendation based on the identity of the vehicle user and the anthropometry information, and cause a vehicle configuration change that modifies a vehicle system based on the unique user identity, mobility limitations, and predicted use of the vehicle.