- 专利标题: Stable liquid pharmaceutical preparation
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申请号: US16310585申请日: 2017-06-28
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公开(公告)号: US11951207B2公开(公告)日: 2024-04-09
- 发明人: Joon Won Lee , Won Yong Han , Su Jung Kim , Jun Seok Oh , So Young Kim , Su Hyeon Hong , Yeon Kyeong Shin
- 申请人: Celltrion Inc.
- 申请人地址: KR Incheon
- 专利权人: Celltrion Inc.
- 当前专利权人: Celltrion Inc.
- 当前专利权人地址: KR Incheon
- 代理机构: Wood, Phillips, Katz, Clark & Mortimer
- 优先权: KR 20160083039 2016.06.30
- 国际申请: PCT/KR2017/006855 2017.06.28
- 国际公布: WO2018/004260A 2018.01.04
- 进入国家日期: 2018-12-17
- 主分类号: A61K9/08
- IPC分类号: A61K9/08 ; A61K39/00 ; A61K39/395 ; A61P37/02 ; A61P37/04 ; A61P37/06 ; C07K16/00 ; C07K16/24 ; A61K47/10 ; A61K47/18 ; A61K47/26
摘要:
The present invention provides a stable liquid pharmaceutical formulation containing: an antibody or its antigen-binding fragment; a surfactant; a sugar or its derivative; and a buffer. The stable liquid pharmaceutical formulation according to the present invention has low viscosity while containing a high content of the antibody, has excellent long-term storage stability based on excellent stability under accelerated conditions and severe conditions, and may be administered subcutaneously.
公开/授权文献
- US20210000743A1 STABLE LIQUID PHARMACEUTICAL PREPARATION 公开/授权日:2021-01-07
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