- 专利标题: Therapeutic molecules that bind to LAG3 and PD1
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申请号: US16969905申请日: 2019-02-18
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公开(公告)号: US11951172B2公开(公告)日: 2024-04-09
- 发明人: Carolyn Edwards , Angelica Sette , Isabelle Osuch , Yumin Teng , James Legg , David Escors Murugarren
- 申请人: CRESCENDO BIOLOGICS LIMITED
- 申请人地址: GB Cambridge
- 专利权人: CRESCENDO BIOLOGICS LIMITED
- 当前专利权人: CRESCENDO BIOLOGICS LIMITED
- 当前专利权人地址: GB Cambridge
- 代理机构: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 优先权: GB 02573 2018.02.16
- 国际申请: PCT/GB2019/050425 2019.02.18
- 国际公布: WO2019/158942A 2019.08.22
- 进入国家日期: 2020-08-13
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61K47/68 ; C07K16/18 ; C07K16/28 ; C12N15/10 ; C07K16/46
摘要:
The invention relates to LAG-3 binding agents, in particular variable heavy chain (VH) sdAbs and bispecific agents that target both LAG-3 and PD-1, and the use of such binding agents in the treatment, prevention and detection of disease.
公开/授权文献
- US20210015937A1 THERAPEUTIC MOLECULES THAT BIND TO LAG3 AND PD1 公开/授权日:2021-01-21
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