An aspect of some embodiments of the invention relate to a system for tissue characterization using an acousto-electric effect comprising: at least one ultrasonic waveform generator; at least one waveform generation controller; at least one set of electrodes; at least one electric signal amplification circuitry connectable to at least one of said at least one set of electrodes to generate an amplified signal; and at least one signal processing unit for analyzing said amplified signal and to generate information related to properties of multiple locations within a target tissue; wherein at least one of said multiple location has no direct contact with any electrode, and wherein said properties of said multiple locations are obtained within up to 10 milliseconds per location on average.