- 专利标题: Immunodeficiency virus type 1 (HIV-1) mutant envelope proteins
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申请号: US17190569申请日: 2021-03-03
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公开(公告)号: US11896663B2公开(公告)日: 2024-02-13
- 发明人: Johannes Petrus Maria Langedijk , Danielle Van Manen , Jort Vellinga , Frank Wegmann , Benoit Christophe Stephan Callendret , Anders Krarup , Jörn Stitz
- 申请人: Janssen Vaccines & Prevention B.V.
- 申请人地址: NL Leiden
- 专利权人: Janssen Vaccines & Prevention B.V.
- 当前专利权人: Janssen Vaccines & Prevention B.V.
- 当前专利权人地址: NL Leiden
- 代理机构: Ice Miller LLP
- 优先权: EP 200138 2015.12.15 EP 194124 2016.10.17
- 分案原申请号: US16440463 2019.06.13
- 主分类号: A61K39/21
- IPC分类号: A61K39/21 ; C07K14/16 ; C07K14/005 ; C12N7/00 ; C12N15/86 ; C12N15/861 ; A61K39/00
摘要:
Compositions and vaccine combinations containing synthetic HIV envelope proteins, and methods for inducing an immune response against human immunodeficiency virus (HIV) infection are described. Viral expression vectors encoding the synthetic HIV envelope proteins can be used in the vaccine combinations to induce immune responses against HIV and provide improved protective immunity against HIV.
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