- 专利标题: Scalable manufacturing platform for viral vector purification and viral vectors so purified for use in gene therapy
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申请号: US17016993申请日: 2020-09-10
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公开(公告)号: US11878056B2公开(公告)日: 2024-01-23
- 发明人: John Fraser Wright , Guang Qu , Bernd Hauck , Katherine A. High
- 申请人: The Children's Hospital of Philadelphia
- 申请人地址: US PA Philadelphia
- 专利权人: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
- 当前专利权人: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
- 当前专利权人地址: US PA Philadelphia
- 代理机构: Pillsbury Winthrop Shaw Pittman LLP
- 代理商 Robert M. Bedgood
- 主分类号: A61K39/23
- IPC分类号: A61K39/23 ; C12N15/864 ; A61K48/00 ; C12N7/00 ; C12N15/00 ; C07K2/00 ; C12N15/64 ; A61K38/46 ; C12N15/86
摘要:
Methods for preparing highly purified AAV vector formulations are provided. The highly pure AAV formulations described herein are superior for clinical use.
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