- 专利标题: Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway
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申请号: US17876433申请日: 2022-07-28
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公开(公告)号: US11866442B2公开(公告)日: 2024-01-09
- 发明人: Daniel W. Robbins , Arthur T. Sands , Joel McIntosh , Jeffrey Mihalic , Jeffrey Wu , Daisuke Kato , Dahlia Weiss , Ge Peng
- 申请人: NURIX THERAPEUTICS, INC.
- 申请人地址: US CA San Francisco
- 专利权人: NURIX THERAPEUTICS, INC.
- 当前专利权人: NURIX THERAPEUTICS, INC.
- 当前专利权人地址: US CA San Francisco
- 代理机构: Squire Patton Boggs (US) LLP
- 主分类号: C07D487/10
- IPC分类号: C07D487/10 ; C07D413/14 ; C07D491/107 ; C07D498/10 ; C07D471/10 ; C07D401/14 ; C07D417/14 ; C07D487/04
摘要:
The present invention relates to compounds useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
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