A mobile system and method of calibrating an ADAS sensor of a vehicle by aligning a target with the sensor, where a transport vehicle is equipped with a target adjustment stand for transporting to the vehicle, which is initially nominally positioned in front of the target adjustment stand that includes a movable target mount configured to support a target, with the target adjustment stand including one or more actuators for adjusting the position of the target mount. A computer system is used to determine an orientation of the vehicle relative to the target adjustment stand, with the position of the target mount being adjusted based on the determined orientation of the vehicle relative to the target adjustment stand. Upon properly orienting the target mount, and the target supported thereon, a calibration routine is performed whereby the sensor is calibrated using the target.