This system and method provide for manufacturing a multi-material hybrid structure comprising a single- or multi-layer sheet or tube, which are made of metals, fabrics, polymer and their combinations, and at least one layer or body made of formed resin. The methods include a simultaneous forming-injection process that followed with an additional sequence to initiate the forming process along with curing and/or solidification and/or bonding processes. The additional sequence provides a pressure drop inside the cavity using tool movement and or additional deformation of one/or several layers of the sheet using any fluid pressure, suction and/or electromagnetic force. The injection process can be used for any kind of synthetic or bio-based resin with or without fiber reinforcement. It is also integrated with supercritical assisted technology.