- 专利标题： Bifunctional compounds comprising insulin peptides and EGF(A) peptides
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申请号： US17281813申请日： 2019-10-04
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公开(公告)号： US11649269B2公开(公告)日： 2023-05-16
- 发明人: Martin Werner Borchsenius Muenzel , Susanne Hostrup , Gro Klitgaard Povlsen , Mathias Norrman , Thomas Boerglum Kjeldsen , Claudia Ulrich Hjoerringgaard , Peter Madsen
- 申请人： Novo Nordisk A/S
- 申请人地址： DK Bagsvaerd
- 专利权人： Novo Nordisk A/S
- 当前专利权人： Novo Nordisk A/S
- 当前专利权人地址： DK Bagsvaerd
- 代理商 Rosemarie R. Wilk-Orescan
- 优先权： EP 198892 2018.10.05
- 国际申请： PCT/EP2019/076889 2019.10.04
- 国际公布： WO2020/070276A 2020.04.09
- 进入国家日期： 2021-03-31
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/62 ; C07K14/485
摘要：
The present invention relates to novel covalently linked bi-functional fusion proteins comprising insulin and EGF(A) analogues or derivatives thereof, and their pharmaceutical use. Furthermore, the invention relates to pharmaceutical compositions comprising such bi-functional compounds, and to the use of such compounds for the treatment or prevention of medical conditions relating to diabetes and dyslipidaemia associated with diabetes.
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