- 专利标题: Technologies for oligonucleotide preparation
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申请号: US16648146申请日: 2018-09-17
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公开(公告)号: US11608355B2公开(公告)日: 2023-03-21
- 发明人: Keith Andrew Bowman , Chandra Vargeese , David Charles Donnell Butler , Pachamuthu Kandasamy , Mohammed Rowshon Alam , Mamoru Shimizu , Stephany Michelle Standley , Vincent Aduda , Gopal Reddy Bommineni , Snehlata Tripathi , Ilia Korboukh
- 申请人: WAVE LIFE SCIENCES LTD.
- 申请人地址: SG Singapore
- 专利权人: WAVE LIFE SCIENCES LTD.
- 当前专利权人: WAVE LIFE SCIENCES LTD.
- 当前专利权人地址: SG Singapore
- 代理机构: Choate, Hall & Stewart LLP
- 代理商 Brenda Herschbach Jarrell; Xiaodong Li
- 国际申请: PCT/US2018/051398 WO 20180917
- 国际公布: WO2019/055951 WO 20190321
- 主分类号: C07H21/02
- IPC分类号: C07H21/02 ; C07H21/04
摘要:
Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs.
公开/授权文献
- US20200231620A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION 公开/授权日:2020-07-23
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