- 专利标题: Peptide nucleic acid conjugates
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申请号: US16889495申请日: 2020-06-01
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公开(公告)号: US11603388B2公开(公告)日: 2023-03-14
- 发明人: Rui Hong , Aoune Barhoumi
- 申请人: Ventana Medical Systems, Inc.
- 申请人地址: US AZ Tucson
- 专利权人: Ventana Medical Systems, Inc.
- 当前专利权人: Ventana Medical Systems, Inc.
- 当前专利权人地址: US AZ Tucson
- 代理机构: Charney IP Law LLC
- 代理商 Thomas M. Finetti
- 主分类号: C07K14/00
- IPC分类号: C07K14/00 ; C07H21/00
摘要:
The present disclosure is directed to conjugates of a specific binding entity and an oligomer, i.e. [Specific Binding Entity]-[Oligomer]n, wherein n is an integer ranging from 1 to 12, and where the Oligomer includes, in some embodiments, a PNA sequence having at least one substituent at a gamma carbon position. In some embodiments, the substituent at the gamma carbon position, e.g. an amino acid, a peptide, a miniPEG, or a polymer, includes at least one reporter moiety.
公开/授权文献
- US20200339633A1 PEPTIDE NUCLEIC ACID CONJUGATES 公开/授权日:2020-10-29
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