Distributed antenna systems (DAS) and methods are disclosed that are aware of cellular user/antenna relationships. The DAS systems and/or methods include or use one or more User Aware Units that provide the functionality of knowing (or, knowledge of) which cellular user(s) each antenna can communicate with (and vice versa). The User Aware Unit functions to gather information about the reception in each antenna in order to identify the cellular users that the respective antenna can communicate with or best communicate with compared to other cellular users.