![[1.1.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors](/docs/US/2022-10-25/US11478461B2/abs.jpg.600x600.jpg)
- 专利标题： [1.1.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors
-
申请号： US17047247申请日： 2019-04-15
-
公开(公告)号： US11478461B2公开(公告)日： 2022-10-25
- 发明人: Liangqin Guo , Hongjun Zhang , Ping Chen , Dane Clausen , Xavier Fradera , Yongxin Han , Shuwen He , Xianhai Huang , Alexander Pasternak , Qinglin Pu , Li Xiao , Feng Ye
- 申请人： Merck Sharp & Dohme Corp.
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 Baerbel R. Brown; Catherine D. Fitch
- 国际申请： PCT/US2019/027425 WO 20190415
- 国际公布： WO2019/204180 WO 20191024
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; A61K45/06 ; C07C237/22 ; C07C255/60 ; C07D213/75 ; C07C271/36 ; C07C233/78 ; C07C271/24 ; C07C233/79 ; C07D213/81 ; C07D271/06 ; C07D239/28 ; C07D215/48 ; C07C275/30 ; C07C275/28 ; C07D239/42 ; C07D305/06 ; C07D261/08 ; C07D471/04 ; C07D261/20 ; C07D209/34 ; C07D277/56 ; C07D217/02 ; C07D231/14 ; C07D237/28 ; C07D241/24 ; C07D217/26 ; A61K31/167 ; A61K31/27 ; A61K31/4245 ; A61K31/47 ; A61K31/17 ; A61K31/505 ; A61K31/337 ; A61K31/437 ; A61K31/42 ; A61K31/426 ; A61K31/472 ; A61K31/415 ; A61K31/4965
![[1.1.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors](/abs-image/US/2022/10/25/US11478461B2/abs.jpg.150x150.jpg)
摘要：
Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.
公开/授权文献
信息查询
