- 专利标题: Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells
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申请号: US16474383申请日: 2018-01-05
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公开(公告)号: US11471494B2公开(公告)日: 2022-10-18
- 发明人: Dean Falb , Jonathan W. Kotula , Vincent M. Isabella , Paul F. Miller , Suman Machinani , Saurabh Saha , Adam B. Fisher , Yves Millet , Ning Li , Jose M. Lora
- 申请人: Synlogic Operating Company, Inc.
- 申请人地址: US MA Cambridge
- 专利权人: Synlogic Operating Company, Inc.
- 当前专利权人: Synlogic Operating Company, Inc.
- 当前专利权人地址: US MA Cambridge
- 代理机构: McCarter & English, LLP
- 代理商 Marcie B. Clarke
- 国际申请: PCT/US2018/012698 WO 20180105
- 国际公布: WO2018/129404 WO 20180712
- 主分类号: A61K35/74
- IPC分类号: A61K35/74 ; C07K14/52 ; C07K14/525 ; C07K14/53 ; C07K14/54 ; C07K14/57 ; C07K14/705 ; C07K16/28 ; C12N9/26 ; C12N15/62 ; C12N15/74 ; A61K33/243
摘要:
Genetically programmed microorganisms, such as bacteria or virus, pharmaceutical compositions thereof, and methods of modulating and treating cancers are disclosed.
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