- 专利标题： Cyanobacterial hosts and methods for producing chemicals
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申请号： US16634027申请日： 2018-07-27
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公开(公告)号： US11352601B2公开(公告)日： 2022-06-07
- 发明人: Yousong Ding , Guang Yang
- 申请人： University of Florida Research Foundation, Incorporated
- 申请人地址： US FL Gainesville
- 专利权人： University of Florida Research Foundation, Incorporated
- 当前专利权人： University of Florida Research Foundation, Incorporated
- 当前专利权人地址： US FL Gainesville
- 代理机构： Wolf, Greenfield & Sacks, P.C.
- 国际申请： PCT/US2018/043993 WO 20180727
- 国际公布： WO2019/023524 WO 20190131
- 主分类号： C12N15/52
- IPC分类号： C12N15/52 ; C12N1/12 ; C12N9/12 ; C12R1/89
摘要：
The present invention relates to recombinant cyanobacterial cells for the production of a chemical compound of interest. In particular, the present invention relates to genetic modifications that introduce one or more heterologous phosphopantetheinyl transferases (PPTases) into a cyanobacterial cell. These cells can, optionally, further comprise heterologous carrier protein and nucleic acid constructs that provide the cyanobacterial cells with the capability of producing chemicals of interest or compounds of interest, such secondary metabolites polyketides, nonribosomal peptides and their hybrids, the three major families of bioactive natural products, of cyanobacteria and other bacterial phyla, secondary metabolites analogs, and unnatural compounds.
公开/授权文献
- US20210087522A1 CYANOBACTERIAL HOSTS AND METHODS FOR PRODUCING CHEMICALS 公开/授权日：2021-03-25
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