- 专利标题： RNA virus vectors carrying DAI and RIPK3
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申请号： US16315420申请日： 2017-07-05
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公开(公告)号： US11332756B2公开(公告)日： 2022-05-17
- 发明人: Siddharth Balachandran , Roshan Thapa
- 申请人： Institute For Cancer Research
- 申请人地址： US PA Philadelphia
- 专利权人： Institute For Cancer Research
- 当前专利权人： Institute For Cancer Research
- 当前专利权人地址： US PA Philadelphia
- 代理机构： Stradley Ronon Stevens & Young, LLP
- 国际申请： PCT/US2017/040719 WO 20170705
- 国际公布： WO2018/009541 WO 20180111
- 主分类号： C12N15/79
- IPC分类号： C12N15/79 ; C07H21/04 ; C12N15/86 ; A61P37/04 ; A61K39/39 ; C07K14/47 ; C12N9/12 ; A61K39/00
摘要：
RNA virus vectors comprising a gene encoding the DNA-dependent activator of interferon-regulatory factors (DAI) protein, and optionally further comprising a gene encoding the receptor-interacting serine/threonine-protein kinase 3 (RIPK3) may be used therapeutically to induce cell death, as well as an inflammatory immune response, against tumors and virally-infected cells.
公开/授权文献
- US20190211359A1 RNA VIRUS VECTORS CARRYING DAI AND RIPK3 公开/授权日：2019-07-11
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