A piezoresistive detection circuit includes a first transistor, a second transistor, a fixed resistor, and a pressure sensitive resistor, a first end of the fixed resistor is connected with a first voltage signal terminal, and a second end of the fixed resistor is connected with a first node, a first end of the pressure sensitive resistor is connected with the first node, and a second end of the pressure sensitive resistor is grounded, a gate electrode of the first transistor is connected with the first node, a source electrode of the first transistor is connected with a second voltage signal terminal, and a drain electrode of the first transistor is connected with a source electrode of the second transistor, a gate electrode of the second transistor is connected with a scanning signal line, and a drain electrode of the second transistor is connected with a readline.