Described techniques provide for communications using multiple different transmission time intervals (TTIs) while in a configured DRX mode that allows efficient scheduling and allocation of resources, and relatively efficient power usage at a user equipment (UE). In some cases, two or more available TTIs for transmissions between a base station and a UE may be identified, and a DRX cycle configured based at least in part on the available TTIs. During monitoring periods of a configured DRX cycle for a first TTI, the UE may be configured to monitor for control signal transmissions associated with a different TTI duration. In some cases, resources for a shorter TTI may be allocated using a two-stage grant. In some cases, multiple component carriers may be configured for one or more different TTIs, and one component carrier may be used to cross schedule resources on other component carriers.