Apparatus, method, and system for enhancing data prefetching based on non-uniform memory access (NUMA) characteristics are described herein. An apparatus embodiment includes a system memory, a cache, and a prefetcher. The system memory includes multiple memory regions, at least some of which are associated with different NUMA characteristic (access latency, bandwidth, etc.) than others. Each region is associated with its own set of prefetch parameters that are set in accordance to their respective NUMA characteristics. The prefetcher monitors data accesses to the cache and generates one or more prefetch requests to fetch data from the system memory to the cache based on the monitored data accesses and the set of prefetch parameters associated with the memory region from which data is to be fetched. The set of prefetcher parameters may include prefetch distance, training-to-stable threshold, and throttle threshold.