- 专利标题: Drug delivery devices with partial drug delivery member retraction
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申请号: US17278618申请日: 2019-10-07
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公开(公告)号: US11213620B2公开(公告)日: 2022-01-04
- 发明人: Ali Nekouzadeh , Carl Conrath , Scott Robert Gibson , Basel Hasan Taha
- 申请人: AMGEN INC.
- 申请人地址: US CA Thousand Oaks
- 专利权人: AMGEN INC.
- 当前专利权人: AMGEN INC.
- 当前专利权人地址: US CA Thousand Oaks
- 代理机构: Marshall, Gerstein & Borun LLP
- 国际申请: PCT/US2019/055010 WO 20191007
- 国际公布: WO2020/091956 WO 20200507
- 主分类号: A61M5/20
- IPC分类号: A61M5/20 ; A61M5/172 ; A61M5/145 ; A61M5/142
摘要:
Methods, devices, and components are provided to reduce tissue resistive pressure during a subcutaneous drug delivery operation by increasing the size of the injection cavity by partially retracting the drug delivery member after inserting the drug delivery member to a subcutaneous position. The drug delivery devices described herein include a magnetic actuator operably coupled to a primary container assembly including a drug delivery member. Power can be selectively provided to the magnetic actuator by a controller to retract the drug delivery member a predetermined distance to relieve pressure in an injection cavity in a patient. A force sensor can provide the controller with a drug delivery member insertion force. The controller can then estimate a tissue resistive pressure based on the drug delivery member insertion force and determine the predetermined distance for the drug delivery member retraction based on the tissue resistive pressure.
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