- 专利标题： Antibodies directed against programmed death-1 (PD-1)
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申请号： US16346485申请日： 2017-11-01
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公开(公告)号： US11155624B2公开(公告)日： 2021-10-26
- 发明人: David J. King , Marilyn Kehry , Baochuan Huang
- 申请人： ANAPTYSBIO, INC. , TESARO, INC.
- 申请人地址： US CA San Diego; US MA Waltham
- 专利权人： ANAPTYSBIO, INC.,TESARO, INC.
- 当前专利权人： ANAPTYSBIO, INC.,TESARO, INC.
- 当前专利权人地址： US CA San Diego; US MA Waltham
- 代理机构： Fish & Richardson P.C.
- 国际申请： PCT/US2017/059618 WO 20171101
- 国际公布： WO2018/085468 WO 20180511
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K39/395 ; C12N15/63 ; A61K45/06 ; A61K39/00
摘要：
The disclosure provides antibody agents that bind to a programmed death-1 (PD-1) protein. Particular immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide sequences are explicitly provided. Also provided are related nucleic acids, vectors, compositions, and methods of using the anti-PD-1 antibody agent to treat a disorder or disease that is responsive to PD-1 inhibition, such as cancer or an infectious disease.
公开/授权文献
- US20190256600A1 ANTIBODIES DIRECTED AGAINST PROGRAMMED DEATH- 1 (PD-1) 公开/授权日：2019-08-22
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