- 专利标题: Heterologous expression of carbohydrate binding modules and uses thereof for cadaverine production
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申请号: US16648194申请日: 2017-09-22
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公开(公告)号: US11118201B2公开(公告)日: 2021-09-14
- 发明人: Howard Chou , Ling Chen , Xiucai Liu
- 申请人: CATHAY BIOTECH INC. , CIBT America Inc.
- 申请人地址: CN Shanghai; US DE Newark
- 专利权人: CATHAY BIOTECH INC.,CIBT America Inc.
- 当前专利权人: CATHAY BIOTECH INC.,CIBT America Inc.
- 当前专利权人地址: CN Shanghai; US DE Newark
- 代理机构: Marshall, Gerstein & Borun LLP
- 国际申请: PCT/CN2017/102884 WO 20170922
- 国际公布: WO2019/056285 WO 20190328
- 主分类号: C12P13/00
- IPC分类号: C12P13/00 ; C12N1/21 ; C12N9/88 ; C07K19/00 ; C07K14/245 ; C12N1/20
摘要:
The invention provides microorganisms genetically modified to co-overexpress a carbohydrate binding module and lysine decarboxylase polypeptides in a mesophilic host to enhance the production of lysine derivatives by the microorganism, method of generating such microorganism, and methods of producing lysine derivatives using the genetically modified microorganisms.
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