Invention Grant
- Patent Title: Factor XIIa inhibitors
-
Application No.: US16461825Application Date: 2017-11-13
-
Publication No.: US11014920B2Publication Date: 2021-05-25
- Inventor: Jacqueline D. Hicks , Brian Alexander McKittrick , Brent R. Whitehead , Matthew Lombardo , Xiaoqing Han , Jerry A. Taylor , Hong Dong Chu , Sung-Sau So , Peter Orth , Zhicai Wu
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Nicole M. Beeler; John C. Todaro
- International Application: PCT/US2017/061281 WO 20171113
- International Announcement: WO2018/093716 WO 20180524
- Main IPC: C07D417/14
- IPC: C07D417/14 ; A61P7/02 ; C07D401/12 ; C07D409/12 ; C07D409/14 ; C07D417/12
Abstract:
The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIIa inhibitors.
Public/Granted literature
- US20200262831A1 Factor XIIa Inhibitors Public/Granted day:2020-08-20
Information query
