- 专利标题： Engineered HCV E2 immunogens and related vaccine compositions
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申请号： US16938105申请日： 2020-07-24
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公开(公告)号： US11008368B2公开(公告)日： 2021-05-18
- 发明人: Linling He , Jiang Zhu , Erick Giang , Mansun Law , Ian Wilson , Netanel Tzarum
- 申请人： THE SCRIPPS RESEARCH INSTITUTE
- 申请人地址： US CA La Jolla
- 专利权人： THE SCRIPPS RESEARCH INSTITUTE
- 当前专利权人： THE SCRIPPS RESEARCH INSTITUTE
- 当前专利权人地址： US CA La Jolla
- 代理商 Hugh Wang; Thomas Fitting
- 主分类号： C07K14/005
- IPC分类号： C07K14/005 ; C12N7/00 ; A61K39/29 ; A61K47/69 ; A61P31/14
摘要：
The present invention provides novel engineered HCV E2 polypeptide immunogens and related vaccine compositions that display the engineered E2 polypeptides. The invention also provides methods of using such immunogens and vaccine compositions in various therapeutic applications, e.g., for preventing or treating HCV infections.
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