- 专利标题： Bipartite molecules and uses thereof in treating diseases associated with abnormal protein aggregates
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申请号： US15328593申请日： 2015-07-24
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公开(公告)号： US10882890B2公开(公告)日： 2021-01-05
- 发明人: Benjamin Pang-Hsien Tu , Rita Py Chen , Joseph Jen-Tse Huang , Yijuang Chern , Yu-Song Jang , Xiang-Me Lai , Tai-Yan Liao , Te-Hsien Kung
- 申请人： Academia Sinica
- 申请人地址： TW Taipei
- 专利权人： Academia Sinica
- 当前专利权人： Academia Sinica
- 当前专利权人地址： TW Taipei
- 代理机构： Polsinelli PC
- 代理商 Tara A. Nealey; Ron Galant
- 国际申请： PCT/US2015/041921 WO 20150724
- 国际公布： WO2016/014908 WO 20160128
- 主分类号： C07K14/47
- IPC分类号： C07K14/47 ; A61K38/00
摘要：
Bipartite molecules comprising a peptide affinity moiety and at least one charged moiety and uses thereof in reducing formation of abnormal protein aggregate and treating diseases associated with such abnormal protein aggregate, including neurodegenerative disease characterized by formation of protein aggregates.
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