Invention Grant
- Patent Title: Composition for preventing and treating eye diseases including anti-Ang2 antibody
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Application No.: US16473685Application Date: 2017-12-19
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Publication No.: US10745472B2Publication Date: 2020-08-18
- Inventor: Gou Young Koh , Jaeryung Kim , Do Young Park
- Applicant: INSTITUTE FOR BASIC SCIENCE , KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Applicant Address: KR Daejeon KR Daejeon
- Assignee: INSTITUTE FOR BASIC SCIENCE,KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee: INSTITUTE FOR BASIC SCIENCE,KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: KR Daejeon KR Daejeon
- Agency: Lex IP Meister, PLLC
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@5183c639 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@5de0fd52
- International Application: PCT/KR2017/014981 WO 20171219
- International Announcement: WO2018/124582 WO 20180705
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; C07K16/22 ; A61P27/02 ; A61P27/06
Abstract:
The present invention relates to a composition which is for preventing and treating eye diseases and comprises an anti-angiopoietin-2 (Ang2) antibody and, more specifically, to a novel use of an anti-Ang2 antibody as an agent for preventing or treating eye diseases, wherein the anti-Ang2 antibody is specifically coupled to Ang2, is coupled to a Tie2 receptor together with Ang2, and has improved affinity. The composition according to the present invention can be usefully used to develop a treatment agent for macular degeneration, diabetic retinopathy, and glaucoma.
Public/Granted literature
- US20190330324A1 COMPOSITION FOR PREVENTING AND TREATING EYE DISEASES INCLUDING ANTI-ANG2 ANTIBODY Public/Granted day:2019-10-31
Information query
