- 专利标题： Ciclopirox for use in modulation of glucose homeostasis
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申请号： US15264704申请日： 2016-09-14
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公开(公告)号： US10576151B2公开(公告)日： 2020-03-03
- 发明人: Ioulia Chatzistamou , Hippokratis Kiaris , Chrysovalantou Mihailidou
- 申请人： UNIVERSITY OF SOUTH CAROLINA
- 申请人地址： US SC Columbia
- 专利权人： University of South Carolina
- 当前专利权人： University of South Carolina
- 当前专利权人地址： US SC Columbia
- 代理机构： Dority & Manning, P.A.
- 主分类号： A61K31/4418
- IPC分类号： A61K31/4418 ; A61K45/06
摘要：
Modulation of glucose homeostasis by administration of ciclopirox (6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one) is described. Methods can be utilized in treatment of conditions that involve loss of glucose homeostasis, such as diabetes, and in one particular embodiment type II diabetes. Ciclopirox is shown to stimulate p21 expression by mechanisms that are likely p53-independent.
公开/授权文献
- US20170071925A1 Ciclopirox for Use in Modulation of Glucose Homeostasis 公开/授权日：2017-03-16
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