- 专利标题： IR dyes for fluorescence imaging
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申请号： US14949654申请日： 2015-11-23
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公开(公告)号： US10548991B2公开(公告)日： 2020-02-04
- 发明人: Daniel R. Draney , William M. Volcheck , Katie Schaepe , Vassil Elitzin
- 申请人： LI-COR, Inc.
- 申请人地址： US NE Lincoln
- 专利权人： LI-COR, INC.
- 当前专利权人： LI-COR, INC.
- 当前专利权人地址： US NE Lincoln
- 代理机构： Kilpatrick Townsend & Stockton LLP
- 主分类号： A61K49/00
- IPC分类号： A61K49/00 ; C09B23/10 ; A61B5/00 ; A61B5/20
摘要：
A method for organ imaging, comprising: administering to a subject a diagnostic effective amount of 2-((E)-2-((E)-3-(2-((E)-3,3-dimethyl-5-sulfonato-1-(4-sulfonatobutyl)indolin-2-ylidene)ethylidene)-2-phenoxycyclohex-1-en-1-yl)vinyl)-3,3-dimethyl-1-(4-sulfonatobutyl)-3H-indol-1-ium-5-sulfonate or 2-((E)-2-((E)-3-(2-((E)-3,3-dimethyl-5-sulfonato-1-(4-sulfonatobutyl)indolin-2-ylidene)ethylidene)-2-(4-sulfonatophenoxy)cyclohex-1-en-1-yl)vinyl)-3,3-dimethyl-1-(4-sulfonatobutyl)-3H-indol-1-ium-5-sulfonate. In one embodiment, the organ includes one or more of kidney, bladder, liver, gall bladder, spleen, intestine, heart, lungs and muscle.
公开/授权文献
- US20160144058A1 IR DYES FOR FLUORESCENCE IMAGING 公开/授权日：2016-05-26
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