- 专利标题： Substituted amines for treating cardiac diseases
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申请号： US15933889申请日： 2018-03-23
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公开(公告)号： US10543212B2公开(公告)日： 2020-01-28
- 发明人: Nobuyuki Matsunaga , Takashi Nakahata , Yuta Tanaka , Hiroki Takahagi , Yasufumi Miyamoto , Rei Okamoto , Takeshi Yoshikawa , Yoshito Terao , Takafumi Yukawa , Keiko Kakegawa , Yoichi Nishikawa , Terufumi Takagi , Masashi Takahashi , Mallareddy Komandla , Lily Kwok , Joanne Miura , Mark Sabat , Nicholas Scorah , Paul Tanis , John Tyhonas , Phong H. Vu , Haixia Wang , Xiaolun Wang , Junya Shirai , Tomohiro Okawa , Zenyu Shiokawa , Akito Shibuya
- 申请人： Cardurion Pharmaceuticals, LLC
- 申请人地址： US MA Cambridge
- 专利权人： Cardurion Pharmaceuticals, LLC
- 当前专利权人： Cardurion Pharmaceuticals, LLC
- 当前专利权人地址： US MA Cambridge
- 代理机构： Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- 主分类号： C07C211/39
- IPC分类号： C07C211/39 ; A61K31/506 ; A61P9/06 ; A61K31/5377
摘要：
The present invention provides a compound having a CaMKII inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of cardiac diseases (particularly catecholaminergic polymorphic ventricular tachycardia, postoperative atrial fibrillation, heart failure, fatal arrhythmia) and the like.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
公开/授权文献
- US20180280389A1 HETEROCYCLIC COMPOUND 公开/授权日：2018-10-04
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