Provided is a multi-master collision prevention system including: a plurality of functional blocks including a plurality of external modules and a plurality of internal modules performing different functions; a plurality of interfaces respectively connected to the plurality of external modules, respectively; a plurality of dedicated registers including priority information of the plurality of functional blocks and connected to the plurality of functional blocks, respectively; a common block selectively connected to the plurality of functional blocks, and configured to function as a master for controlling the common blocks when the plurality of functional blocks are connected to the common block; and a priority determination unit configured to determine a connection between any one of the plurality of functional blocks and the common block.