Invention Grant
- Patent Title: Antagonistic CTLA-4 aptamers and applications thereof in enhancing immune activity
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Application No.: US15500345Application Date: 2015-07-31
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Publication No.: US10533179B2Publication Date: 2020-01-14
- Inventor: Konan Peck , Pan-Chyr Yang , Yi-Chung Chang , Bo-Tsang Huang , Shauh-Der Yeh
- Applicant: Academia Sinica , National Taiwan University , Taipei Medical University
- Applicant Address: TW Taipei TW Taipei TW Taipei
- Assignee: Academia Sinica,National Taiwan University,Taipei Medical University
- Current Assignee: Academia Sinica,National Taiwan University,Taipei Medical University
- Current Assignee Address: TW Taipei TW Taipei TW Taipei
- Agency: Polsinelli
- International Application: PCT/US2015/043133 WO 20150731
- International Announcement: WO2016/019255 WO 20160204
- Main IPC: C12N15/115
- IPC: C12N15/115 ; C12N15/113 ; A61K31/711 ; A61K9/00 ; A61K31/713 ; A61K47/60
Abstract:
Aptamers that bind to and inhibit CTLA-4 and uses thereof in enhancing immune activities, and treating cancer and HIV infection are provided.
Public/Granted literature
- US20170211067A1 ANTAGONISTIC CTLA-4 APTAMERS AND APPLICATIONS THEREOF IN ENHANCING IMMUNE ACTIVITY Public/Granted day:2017-07-27
Information query
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