- 专利标题: Proteostasis regulators
-
申请号: US15402628申请日: 2017-01-10
-
公开(公告)号: US10532996B2公开(公告)日: 2020-01-14
- 发明人: Megan Foley , Bradley Tait , Matthew Cullen
- 申请人: Proteostasis Therapeutics, Inc.
- 申请人地址: US MA Cambridge
- 专利权人: Proteostasis Therapeutics, Inc.
- 当前专利权人: Proteostasis Therapeutics, Inc.
- 当前专利权人地址: US MA Cambridge
- 代理机构: Armstrong Teasdale, LLP
- 主分类号: C07D403/06
- IPC分类号: C07D403/06 ; C07D405/06 ; C07D401/06 ; C07D249/06 ; C07D207/333 ; C07D207/337 ; C07D231/12 ; C07D263/32 ; C07D275/02 ; C07D295/185 ; C07D333/20 ; C07D471/04 ; C07D333/22
摘要:
The present invention is directed to compounds having the Formulae (Ia-Ie), (II), (IIIa-IIId), (IVa-IVc), (Va-Vb), (VIa-VIe), (VII), (VIIIa-VIIIc), and (IX), pharmaceutically acceptable salts, prodrugs and solvates thereof, compositions of any of thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis comprising an effective amount of these compounds.
公开/授权文献
- US20170247355A1 PROTEOSTASIS REGULATORS 公开/授权日:2017-08-31
信息查询