A method, computer system, and a computer program product for optimizing speech recognition in a smart medical room. The present invention may include receiving a piece of verbal data associated with a medical encounter from one or more audio recording devices. The present invention may also include accessing a plurality of signals from a plurality of biometric sensors associated with a plurality of medical equipment associated with the smart medical room based on the received piece of verbal data associated with the medical encounter. The present invention may further include selecting, from a database, one or more speech domain models based on the accessed plurality of signals from the plurality of biometric sensors associated with the plurality of medical equipment, wherein the one or more speech domain models are utilized to optimize a transcription of speech during the medical encounter in the smart medical room.