Invention Grant
- Patent Title: Antiproliferative compounds and conjugates made therefrom
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Application No.: US15789027Application Date: 2017-10-20
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Publication No.: US10398783B2Publication Date: 2019-09-03
- Inventor: Ivar M. McDonald , Prasanna Sivaprakasam , Christiana I. Iwuagwu , Kevin M. Peese , Heng Cheng , Naidu S. Chowdari , Sanjeev Gangwar
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Yuan Chao
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K47/68 ; C07D519/00 ; C07F7/08 ; C07K5/062
Abstract:
A compound capable of inhibiting cell proliferation, having a structure according to formula (I) wherein the variables in formula (I) are as defined in the specification. Such compounds are useful as anti-cancer agents, especially in antibody-drug conjugates.
Public/Granted literature
- US20180110873A1 ANTIPROLIFERATIVE COMPOUNDS AND CONJUGATES MADE THEREFROM Public/Granted day:2018-04-26
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