Invention Grant
- Patent Title: Method of selectively releasing nitric oxide depending on change in pH using calcium phosphate
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Application No.: US15359474Application Date: 2016-11-22
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Publication No.: US10301332B2Publication Date: 2019-05-28
- Inventor: Won Jong Kim , Jihoon Kim , Hyung Woo Choi
- Applicant: INSTITUTE FOR BASIC SCIENCE , POSTECH ACADEMY-INDUSTRY FOUNDATION
- Applicant Address: KR Daejeon KR Gyeongsangbuk-do
- Assignee: Institute for Basic Science,Postech Academy-Industry Foundation
- Current Assignee: Institute for Basic Science,Postech Academy-Industry Foundation
- Current Assignee Address: KR Daejeon KR Gyeongsangbuk-do
- Agency: McCoy Russell LLP
- Priority: KR10-2015-0163839 20151123
- Main IPC: C07F7/18
- IPC: C07F7/18 ; B01J20/04 ; B01J20/22 ; A61K33/00 ; C01B21/24 ; A61K31/655 ; A61K31/695 ; A61K47/54 ; A61K47/69 ; B82Y5/00
Abstract:
Provided is a method of controlling release of nitric oxide, and more particularly, to a method of selectively releasing nitric oxide depending on a change in pH using calcium phosphate.The method of selectively releasing nitric oxide according to the present invention may stably deliver nitric oxide to a desired site, and induce release of nitric oxide by a change in pH, thereby making it possible to improve a therapeutic effect while preventing a loss of nitric oxide.
Public/Granted literature
- US20170145040A1 METHOD OF SELECTIVELY RELEASING NITRIC OXIDE DEPENDING ON CHANGE IN PH USING CALCIUM PHOSPHATE Public/Granted day:2017-05-25
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