A marine pipeline installation system and marine pipeline installation method are disclosed. The marine pipeline installation system includes a pipeline launch tower for launching the pipeline in a firing line along the pipeline launch tower into the sea, and one or more tensioners supported by the pipeline launch tower. The system further includes a pipeline guide supported in a pipeline launch trajectory between a pipeline storage and the firing line above the one or more tensioners, wherein the pipeline guide is provided opposite the firing line relative to the pipeline launch tower. A guide support structure is provided, which is embodied as a single-sided guide support arm arranged on one side of the pipeline guide only.