- 专利标题： Mitochondrial uncouplers for treatment of metabolic diseases and cancer
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申请号： US15599177申请日： 2017-05-18
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公开(公告)号： US10227315B2公开(公告)日： 2019-03-12
- 发明人: Shengkan Jin , David J. Augeri , Bin Cao , Hanlin Tao
- 申请人： RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
- 申请人地址： US NJ New Brunswick
- 专利权人： RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
- 当前专利权人： RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
- 当前专利权人地址： US NJ New Brunswick
- 代理机构： Pepper Hamilton LLP
- 主分类号： C07D277/82
- IPC分类号： C07D277/82 ; C07D417/04 ; C07D417/12 ; A61K31/167 ; A61K31/277 ; A61K31/428 ; A61K31/4545 ; A61K31/496 ; A61K31/536 ; A61K31/5375 ; A61K31/5377 ; A61K31/675 ; A61K45/06 ; C07C235/64 ; C07C255/60 ; C07D241/20 ; C07D295/205 ; C07F9/6541
摘要：
The present disclosure relates to benzamide compounds, prodrugs of the compounds, pharmaceutical compositions containing the compounds and/or the prodrugs and methods of using the compounds, prodrugs and pharmaceutical compositions in the treatment of diseases related to lipid metabolism including diabetes, Non-Alcholic Fatty Liver Disease (NAFLD), Non-Alcholic Steathohepatitis (NASH), diseases caused by abnormal cell proliferation including cancer, psoriasis, and infectious diseases.
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