- 专利标题： Heterocyclic modulators of HIF activity for treatment of disease
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申请号： US15285177申请日： 2016-10-04
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公开(公告)号： US10208059B2公开(公告)日： 2019-02-19
- 发明人: Philip Jones , Maria Emilia Di Francesco , Alessia Petrocchi , Christopher L. Carroll , Joe Marszalek , Barbara Czako , Ryan Johnson , Jay Theroff
- 申请人： Board of Regents, University of Texas System
- 申请人地址： US TX Austin
- 专利权人： Board of Regents, The University of Texas System
- 当前专利权人： Board of Regents, The University of Texas System
- 当前专利权人地址： US TX Austin
- 代理商 Dennis A. Bennett; Cynthia Hathaway; John Desper
- 主分类号： C07D413/14
- IPC分类号： C07D413/14 ; C07D495/04 ; C07D413/04 ; C07D417/14 ; C07D417/04 ; A61K45/06 ; A61K31/496 ; A61K31/454 ; C07D471/04 ; C07D513/04 ; A61K31/4245 ; A61K31/437 ; A61K31/4439 ; A61K31/4545 ; A61K31/519 ; A61K31/5377 ; A61K31/541 ; C07D405/14 ; A61K31/427 ; A61K31/4709 ; A61K31/497 ; A61K31/506
摘要：
The present invention relates to compounds and methods which may be useful as inhibitors of HIF pathway activity for the treatment or prevention of cancer and other hypoxia-mediated diseases.
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