- 专利标题: Compounds and methods of treating ocular disorders
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申请号: US15634159申请日: 2017-06-27
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公开(公告)号: US10208049B2公开(公告)日: 2019-02-19
- 发明人: Krzysztof Palczewski , Akiko Maeda , Marcin Golczak
- 申请人: Case Western Reserve University
- 申请人地址: US OH Cleveland
- 专利权人: Case Western Reserve University
- 当前专利权人: Case Western Reserve University
- 当前专利权人地址: US OH Cleveland
- 代理机构: Cooley LLP
- 代理商 Heidi A. Erlacher; Chen Chen
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; A61K31/4162 ; A61K31/4184 ; A61K31/428 ; A61K31/56 ; C07C211/01 ; C07C229/12 ; C07C229/60 ; C07C229/64 ; C07C237/48 ; C07C251/58 ; C07C317/36 ; C07D261/04 ; A61K9/00
摘要:
A method of treating an ocular disorder in a subject associated with aberrant all-trans-retinal clearance in the retina, the method comprising administering to the subject a therapeutically effective amount of a primary amine compound of formula: wherein R1 is an aliphatic and/or aromatic compound.
公开/授权文献
- US20180134714A1 COMPOUNDS AND METHODS OF TREATING OCULAR DISORDERS 公开/授权日:2018-05-17
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