The utility model discloses a high low temperature temperature control device, including pressure chamber (1) and temperature measurement and control system, pressure chamber (1) constitute by box andtop cap (10), be provided with rotatable folding paper on the box, the box links to each other with switch door (3) through rotatable folding paper, switch door (3) openly are provided with temperature measurement and control appearance (5), temperature sensor (2) are installed to the bottom in the box, middle part corner sets in the box has backing sheet (8), it places on backing sheet (8) through switch door (3) to hold ware (9), box top four corners all is provided with arch (6), be provided with the screw hole in protruding (6). The utility model discloses the utilization sets up miniature air conditioner at the box top to install the indoor set in the top cap, the off -premises station is installed outside the top cap, has realized temperature regulation and control simple accurate,satisfies the requirement of quick experiment, has practiced thrift experiment preparation time.